New Study Further Links Oxytocin Deficits to Schizophrenia

New research has given further hope that oxytocin spray my form the base of future treatments for schizophrenia.


Higher doses of second-generation antipsychotics and more severe negative symptoms are associated with lower levels of oxytocin in cerebrospinal fluid among patients with schizophrenia, researchers report.

The findings, published in Schizophrenia Research, are “in line with the possibility that central oxytocin may ameliorate the severity of some symptoms of schizophrenia by improving social functioning,” say Daimei Sasayama (National Center of Neurology and Psychiatry, Tokyo, Japan) and team.

Despite the mounting evidence of a link between a deficit of oxytocin in the brain and the distressing symptoms of schizophrenia, both prmary (voices and delusions) and secondary (lack of social functioning), we still appear to be years away from a prescription medication for schizophrenia based upon oxytocin.